iRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity

BACKGROUND: Tamoxifen (Tam) is the most frequent treatment for estrogen receptor (ER) positive breast cancer. We recently showed that fibronectin (FN) leads to Tam resistance and selection of breast cancer stem cells. With the aim of developing a nanoformulation that would simultaneously tackle ER a...

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Detaylı Bibliyografya
Yayımlandı:J Nanobiotechnology
Asıl Yazarlar: Diaz Bessone, María Inés, Simón-Gracia, Lorena, Scodeller, Pablo, Ramirez, María de los Angeles, Lago Huvelle, María Amparo, Soler-Illia, Galo J. A. A., Simian, Marina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898937/
https://ncbi.nlm.nih.gov/pubmed/31812165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0553-4
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