Φορτώνει......
iRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity
BACKGROUND: Tamoxifen (Tam) is the most frequent treatment for estrogen receptor (ER) positive breast cancer. We recently showed that fibronectin (FN) leads to Tam resistance and selection of breast cancer stem cells. With the aim of developing a nanoformulation that would simultaneously tackle ER a...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Nanobiotechnology |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6898937/ https://ncbi.nlm.nih.gov/pubmed/31812165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0553-4 |
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