Prevalence and Impact of Treatment Crossover in Cardiac Surgery Randomized Trials: A Meta‐Epidemiologic Study

BACKGROUND: Crossover dilutes treatment effect and reduces statistical power of intention‐to‐treat analysis. We examined incidence and impact on cardiac surgery randomized controlled trial (RCT) outcomes of crossover from experimental to control interventions, or vice versa. METHODS AND RESULTS: MED...

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Bibliografische gegevens
Gepubliceerd in:J Am Heart Assoc
Hoofdauteurs: Gaudino, Mario, Fremes, Stephen E., Ruel, Marc, Di Franco, Antonino, Di Mauro, Michele, Chikwe, Joanna, Frati, Giacomo, Girardi, Leonard N., Taggart, David P., Biondi‐Zoccai, Giuseppe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Systematic Review and Meta‐analysis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898839/
https://ncbi.nlm.nih.gov/pubmed/31663420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013711
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