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Prevalence and Impact of Treatment Crossover in Cardiac Surgery Randomized Trials: A Meta‐Epidemiologic Study

BACKGROUND: Crossover dilutes treatment effect and reduces statistical power of intention‐to‐treat analysis. We examined incidence and impact on cardiac surgery randomized controlled trial (RCT) outcomes of crossover from experimental to control interventions, or vice versa. METHODS AND RESULTS: MED...

詳細記述

保存先:
書誌詳細
出版年:J Am Heart Assoc
主要な著者: Gaudino, Mario, Fremes, Stephen E., Ruel, Marc, Di Franco, Antonino, Di Mauro, Michele, Chikwe, Joanna, Frati, Giacomo, Girardi, Leonard N., Taggart, David P., Biondi‐Zoccai, Giuseppe
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898839/
https://ncbi.nlm.nih.gov/pubmed/31663420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013711
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