N-Methyl-D-aspartate receptor antagonist d-methadone produces rapid, mTORC1-dependent antidepressant effects

Currently available antidepressants have a delayed onset and limited efficacy, highlighting the need for new, rapid and more efficacious agents. Ketamine, an NMDA receptor antagonist, has emerged as a new rapid-acting antidepressant, effective even in treatment resistant patients. However, ketamine...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuropsychopharmacology
Egile Nagusiak: Fogaça, Manoela V., Fukumoto, Kenichi, Franklin, Tina, Liu, Rong-Jian, Duman, Catharine H., Vitolo, Ottavio V., Duman, Ronald S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898593/
https://ncbi.nlm.nih.gov/pubmed/31454827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0501-x
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