LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS

The evolutionary processes that drive universal therapeutic resistance in adult patients with diffuse glioma remain unclear(1,2). Here, we analyzed temporally separated DNA sequencing data and matched clinical annotation from 222 patients with glioma. Through mutational and copy number analyses acro...

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Publicado en:Nature
Main Authors: Barthel, Floris P., Johnson, Kevin C., Varn, Frederick S., Moskalik, Anzhela D., Tanner, Georgette, Kocakavuk, Emre, Anderson, Kevin J., Abiola, Olajide, Aldape, Kenneth, Alfaro, Kristin D., Alpar, Donat, Amin, Samirkumar B., Ashley, David M., Bandopadhayay, Pratiti, Barnholtz-Sloan, Jill S., Beroukhim, Rameen, Bock, Christoph, Brastianos, Priscilla K., Brat, Daniel J., Brodbelt, Andrew R., Bruns, Alexander F., Bulsara, Ketan R., Chakrabarty, Aruna, Chakravarti, Arnab, Chuang, Jeffrey H., Claus, Elizabeth B., Cochran, Elizabeth J., Connelly, Jennifer, Costello, Joseph F., Finocchiaro, Gaetano, Fletcher, Michael N., French, Pim J., Gan, Hui K., Gilbert, Mark R., Gould, Peter V., Grimmer, Matthew R., Iavarone, Antonio, Ismail, Azzam, Jenkinson, Michael D., Khasraw, Mustafa, Kim, Hoon, Kouwenhoven, Mathilde C.M., LaViolette, Peter S., Li, Meihong, Lichter, Peter, Ligon, Keith L., Lowman, Allison K., Malta, Tathiane M., Mazor, Tali, McDonald, Kerrie L., Molinaro, Annette M., Nam, Do-Hyun, Nayyar, Naema, Ng, Ho Keung, Ngan, Chew Yee, Niclou, Simone, P., Niers, Johanna M., Noushmehr, Houtan, Noorbakhsh, Javad, Ormond, D. Ryan, Park, Chul-Kee, Poisson, Laila M., Rabadan, Raul, Radlwimmer, Bernhard, Rao, Ganesh, Reifenberger, Guido, Sa, Jason K., Schuster, Michael, Shaw, Brian L., Short, Susan C., Sillevis Smitt, Peter A., Sloan, Andrew E., Smits, Marion, Suzuki, Hiromichi, Tabatabai, Ghazaleh, Van Meir, Erwin G., Watts, Colin, Weller, Michael, Wesseling, Pieter, Westerman, Bart A., Widhalm, Georg, Woehrer, Adelheid, Alfred Yung, W.K., Zadeh, Gelareh, Huse, Jason T., de Groot, John F., Stead, Lucy F., Verhaak, Roel G.W.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897368/
https://ncbi.nlm.nih.gov/pubmed/31748746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1775-1
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