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The chemical synthesis of human milk oligosaccharides: lacto-N-tetraose (Galβ1→3GlcNAcβ1→3Galβ1→4Glc)

The total chemical synthesis of lacto-N-tetraose (LNT) has been completed using both convergent and linear strategies. Similarly to that of our previous HMO syntheses, the donor-acceptor protecting-leaving group combinations were found to be of paramount significance to achieving successful glycosyl...

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Publicat a:Carbohydr Res
Autors principals: Bandara, Mithila D., Stine, Keith J., Demchenko, Alexei V.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897367/
https://ncbi.nlm.nih.gov/pubmed/31585319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2019.107824
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