Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

BACKGROUND: Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety and analgesic efficacy of tanezumab, a humanized monoclonal antibody that binds and inhibits nerve growth factor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:N Engl J Med
Prif Awduron: Lane, Nancy E., Schnitzer, Thomas J., Birbara, Charles A., Mokhtarani, Masoud, Shelton, David L., Smith, Mike D., Brown, Mark T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896791/
https://ncbi.nlm.nih.gov/pubmed/20942668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0901510
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