First-in-human randomized clinical trials of the safety and efficacy of tanezumab for treatment of chronic knee osteoarthritis pain or acute bunionectomy pain

INTRODUCTION: The neurotrophin nerve growth factor has a demonstrated role in pain transduction and pathophysiology. OBJECTIVES: Two randomized, double-blind, placebo-controlled, phase 1 studies were conducted to evaluate safety, tolerability, and analgesic efficacy of single doses of tanezumab, a h...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pain Rep
Hauptverfasser: Walicke, Patricia A., Hefti, Franz, Bales, Roxanne, Lu, Shiao-Ping, Ruckle, Jon L., Brown, Mark T., West, Christine R., Shelton, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2018
Schlagworte:
Musculoskeletal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999411/
https://ncbi.nlm.nih.gov/pubmed/29922745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000653
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge