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Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee
BACKGROUND: Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety and analgesic efficacy of tanezumab, a humanized monoclonal antibody that binds and inhibits nerve growth factor...
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| Pubblicato in: | N Engl J Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6896791/ https://ncbi.nlm.nih.gov/pubmed/20942668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0901510 |
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