The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration

CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutations within the CBP gene are known to cause Rubinstein-Taybi syndrome (RSTS), a developmental...

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Publicado en:Acta Neuropathol Commun
Autores principales: Schoof, Melanie, Launspach, Michael, Holdhof, Dörthe, Nguyen, Lynhda, Engel, Verena, Filser, Severin, Peters, Finn, Immenschuh, Jana, Hellwig, Malte, Niesen, Judith, Mall, Volker, Ertl-Wagner, Birgit, Hagel, Christian, Spohn, Michael, Lutz, Beat, Sedlacik, Jan, Indenbirken, Daniela, Merk, Daniel J., Schüller, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896766/
https://ncbi.nlm.nih.gov/pubmed/31806049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0849-5
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