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Roxatidine inhibits fibrosis by inhibiting NF-κB and MAPK signaling in macrophages sensing breast implant surface materials

Capsular contracture is an important complication after silicone mammary implant surgery. Fibroblasts and macrophages play critical roles in the pathogenesis of capsular contracture, making these two cell types therapeutic targets. It has been reported that inhibiting histamine receptors results att...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Ji, Litong, Wang, Tie, Tian, Lining, Song, Hongjiang, Gao, Meizhuo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896367/
https://ncbi.nlm.nih.gov/pubmed/31746427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10815
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