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Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation
Roxatidine is an active metabolite of roxatidine acetate hydrochloride which is a histamine H(2)-receptor antagonist that is used to treat gastric and duodenal ulcers. In this study, we investigated the anti-allergic inflammatory effects and the underlying molecular mechanism of roxatidine in phorbo...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282503/ https://ncbi.nlm.nih.gov/pubmed/28139747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41721 |
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