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Roxatidine inhibits fibrosis by inhibiting NF-κB and MAPK signaling in macrophages sensing breast implant surface materials

Capsular contracture is an important complication after silicone mammary implant surgery. Fibroblasts and macrophages play critical roles in the pathogenesis of capsular contracture, making these two cell types therapeutic targets. It has been reported that inhibiting histamine receptors results att...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Ji, Litong, Wang, Tie, Tian, Lining, Song, Hongjiang, Gao, Meizhuo
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896367/
https://ncbi.nlm.nih.gov/pubmed/31746427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10815
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