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A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit

During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) differentiate. Usi...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Sladitschek, Hanna L, Neveu, Pierre A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896232/
https://ncbi.nlm.nih.gov/pubmed/31885203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20199043
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