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A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit

During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) differentiate. Usi...

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Detalles Bibliográficos
Publicado en:Mol Syst Biol
Main Authors: Sladitschek, Hanna L, Neveu, Pierre A
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896232/
https://ncbi.nlm.nih.gov/pubmed/31885203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20199043
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