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Deconstructing the pluripotency gene regulatory network

Pluripotent stem cells can be isolated from embryos or derived by reprogramming. Pluripotency is stabilized by an interconnected network of pluripotency genes that cooperatively regulate gene expression. Here we describe the molecular principles of pluripotency gene function and highlight post-trans...

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Publicat a:Nat Cell Biol
Autors principals: Li, Mo, Belmonte, Juan Carlos Izpisua
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620196/
https://ncbi.nlm.nih.gov/pubmed/29593328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0067-6
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