AXL Receptor Tyrosine Kinase as a Therapeutic Target in Hematological Malignancies: Focus on Multiple Myeloma

AXL belongs to the TAM (TYRO3, AXL, and MERTK) receptor family, a unique subfamily of the receptor tyrosine kinases. Their common ligand is growth arrest-specific protein 6 (GAS6). The GAS6/TAM signaling pathway regulates many important cell processes and plays an essential role in immunity, hemosta...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yan, Siyang, Vandewalle, Niels, De Beule, Nathan, Faict, Sylvia, Maes, Ken, De Bruyne, Elke, Menu, Eline, Vanderkerken, Karin, De Veirman, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896070/
https://ncbi.nlm.nih.gov/pubmed/31694201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111727
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