The Epigenome in Multiple Myeloma: Impact on Tumor Cell Plasticity and Drug Response

Multiple myeloma (MM) is a clonal plasma cell malignancy that develops primarily in the bone marrow (BM), where reciprocal interactions with the BM niche foster MM cell survival, growth, and drug resistance. MM cells furthermore reshape the BM to their own needs by affecting the different BM stromal...

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Bibliographic Details
Published in:Front Oncol
Main Authors: De Smedt, Eva, Lui, Hui, Maes, Ken, De Veirman, Kim, Menu, Eline, Vanderkerken, Karin, De Bruyne, Elke
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297718/
https://ncbi.nlm.nih.gov/pubmed/30619733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00566
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