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Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation

Deregulation of different intracellular signaling pathways is a common feature in cancer. Numerous studies indicate that persistent activation of the phosphoinositide 3-kinase (PI3K) pathway is often observed in cancer cells. 3-phosphoinositide dependent protein kinase-1 (PDK1), a transducer protein...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Casari, Ilaria, Domenichini, Alice, Sestito, Simona, Capone, Emily, Sala, Gianluca, Rapposelli, Simona, Falasca, Marco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896057/
https://ncbi.nlm.nih.gov/pubmed/31683659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111695
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