WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX(7-21) and WWOX(7-11) for Signaling Cancer Growth Suppression and Prevention In Vivo

Membrane hyaluronidase Hyal-2 supports cancer cell growth. Inhibition of Hyal-2 by specific antibody against Hyal-2 or pY216-Hyal-2 leads to cancer growth suppression and prevention in vivo. By immunoelectron microscopy, tumor suppressor WWOX is shown to be anchored, in part, in the cell membrane by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Wang, Wan-Jen, Ho, Pei-Chuan, Nagarajan, Ganesan, Chen, Yu-An, Kuo, Hsiang-Ling, Subhan, Dudekula, Su, Wan-Pei, Chang, Jean-Yun, Lu, Chen-Yu, Chang, Katarina T., Lin, Sing-Ru, Lee, Ming-Hui, Chang, Nan-Shan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895976/
https://ncbi.nlm.nih.gov/pubmed/31752354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111818
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