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PiggyBac transposon system with polymeric gene carrier transfected into human T cells

CAR-T cell-based immunotherapy has shown great promise in clinical trials for the treatment of hematological malignancies. The majority of these trials utilize retroviral and lentiviral vectors to introduce CAR transgene. In spite of its satisfactory efficiency, the concerns about the potential carc...

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Bibliografski detalji
Izdano u:Am J Transl Res
Glavni autori: Zheng, Yan, Li, Zhan-Rong, Yue, Ran, Fu, Yu-Long, Liu, Zi-Yang, Feng, Hua-Yang, Li, Jing-Guo, Han, Shuang-Yin
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895516/
https://ncbi.nlm.nih.gov/pubmed/31814915
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