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PiggyBac transposon system with polymeric gene carrier transfected into human T cells

CAR-T cell-based immunotherapy has shown great promise in clinical trials for the treatment of hematological malignancies. The majority of these trials utilize retroviral and lentiviral vectors to introduce CAR transgene. In spite of its satisfactory efficiency, the concerns about the potential carc...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zheng, Yan, Li, Zhan-Rong, Yue, Ran, Fu, Yu-Long, Liu, Zi-Yang, Feng, Hua-Yang, Li, Jing-Guo, Han, Shuang-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895516/
https://ncbi.nlm.nih.gov/pubmed/31814915
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