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PiggyBac transposon system with polymeric gene carrier transfected into human T cells

CAR-T cell-based immunotherapy has shown great promise in clinical trials for the treatment of hematological malignancies. The majority of these trials utilize retroviral and lentiviral vectors to introduce CAR transgene. In spite of its satisfactory efficiency, the concerns about the potential carc...

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Dettagli Bibliografici
Pubblicato in:Am J Transl Res
Autori principali: Zheng, Yan, Li, Zhan-Rong, Yue, Ran, Fu, Yu-Long, Liu, Zi-Yang, Feng, Hua-Yang, Li, Jing-Guo, Han, Shuang-Yin
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895516/
https://ncbi.nlm.nih.gov/pubmed/31814915
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