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Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation
DNA mismatches are highly polymorphic and dynamic in nature, albeit poorly characterized structurally. We utilized the antitumour antibiotic Co(II)(Chro)(2) (Chro = chromomycin A3) to stabilize the palindromic duplex d(TTGGCGAA) DNA with two G:G mismatches, allowing X-ray crystallography-based monit...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6895262/ https://ncbi.nlm.nih.gov/pubmed/31361900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz653 |
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