Pten haploinsufficiency disrupts scaling across brain areas during development in mice

Haploinsufficiency for PTEN is a cause of autism spectrum disorder and brain overgrowth; however, it is not known if PTEN mutations disrupt scaling across brain areas during development. To address this question, we used magnetic resonance imaging to analyze brains of male Pten haploinsufficient (Pt...

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Publicat a:Transl Psychiatry
Autors principals: Clipperton-Allen, Amy E., Cohen, Ori S., Aceti, Massimiliano, Zucca, Aya, Levy, Jenna, Ellegood, Jacob, Lerch, Jason P., Page, Damon T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895202/
https://ncbi.nlm.nih.gov/pubmed/31804455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0656-6
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