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Autism-Relevant Behaviors Are Minimally Impacted by Conditional Deletion of Pten in Oxytocinergic Neurons

Germline heterozygous mutations in Pten (phosphatase and tensin homolog) are associated with macrocephaly and autism spectrum disorders (ASD). Pten germline heterozygous (Pten(+/−)) mice approximate these mutations, and both sexes show widespread brain overgrowth and impaired social behavior. Striki...

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Detalhes bibliográficos
Publicado no:Autism Res
Main Authors: Clipperton-Allen, Amy E., Chen, Youjun, Page, Damon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467524/
https://ncbi.nlm.nih.gov/pubmed/27220363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/aur.1641
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