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Connecting Genotype with Behavioral Phenotype in Mouse Models of Autism Associated with PTEN Mutations
A subset of individuals with autism spectrum disorder (ASD) and macrocephaly carry mutations in the gene PTEN. Animal models, particularly mice, have been helpful in establishing a causal role for Pten mutations in autism-relevant behavioral deficits. These models are a useful tool for investigating...
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| 發表在: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461765/ https://ncbi.nlm.nih.gov/pubmed/31871231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a037010 |
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