Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

Dysplasia is considered a key transition state between pre-cancer and cancer in gastric carcinogenesis. However, the cellular or phenotypic heterogeneity and mechanisms of dysplasia progression have not been elucidated. We have established metaplastic and dysplastic organoid lines, derived from Mist...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Min, Jimin, Vega, Paige N., Engevik, Amy C., Williams, Janice A., Yang, Qing, Patterson, Loraine M., Simmons, Alan J., Bliton, R. Jarrett, Betts, Joshua W., Lau, Ken S., Magness, Scott T., Goldenring, James R., Choi, Eunyoung
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895174/
https://ncbi.nlm.nih.gov/pubmed/31804471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13479-6
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