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Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
Dysplasia is considered a key transition state between pre-cancer and cancer in gastric carcinogenesis. However, the cellular or phenotypic heterogeneity and mechanisms of dysplasia progression have not been elucidated. We have established metaplastic and dysplastic organoid lines, derived from Mist...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6895174/ https://ncbi.nlm.nih.gov/pubmed/31804471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13479-6 |
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