Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

Dysplasia is considered a key transition state between pre-cancer and cancer in gastric carcinogenesis. However, the cellular or phenotypic heterogeneity and mechanisms of dysplasia progression have not been elucidated. We have established metaplastic and dysplastic organoid lines, derived from Mist...

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Publicat a:Nat Commun
Autors principals: Min, Jimin, Vega, Paige N., Engevik, Amy C., Williams, Janice A., Yang, Qing, Patterson, Loraine M., Simmons, Alan J., Bliton, R. Jarrett, Betts, Joshua W., Lau, Ken S., Magness, Scott T., Goldenring, James R., Choi, Eunyoung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895174/
https://ncbi.nlm.nih.gov/pubmed/31804471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13479-6
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