Is Meropenem as a Monotherapy Truly Incompetent for Meropenem-Nonsusceptible Bacterial Strains? A Pharmacokinetic/Pharmacodynamic Modeling With Monte Carlo Simulation

Infections due to meropenem-nonsusceptible bacterial strains (MNBSs) with meropenem minimum inhibitory concentrations (MICs) ≥ 16 mg/L have become an urgent problem. Currently, the optimal treatment strategy for these cases remains uncertain due to some limitations of currently available mono- and c...

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Publicat a:Front Microbiol
Autors principals: Song, Xiangqing, Wu, Yi, Cao, Lizhi, Yao, Dunwu, Long, Minghui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895071/
https://ncbi.nlm.nih.gov/pubmed/31849910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02777
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