Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Lepr(db)/J mouse model of non-alcoholic fatty liver disease (NAFLD)

Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern. With a propensity to progress towards non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma, NAFLD is an important link amongst a multitude of comorbidities including obesity, diabetes, and cardiova...

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Pubblicato in:PLoS One
Autori principali: Su, Robin C., Lad, Apurva, Breidenbach, Joshua D., Blomquist, Thomas M., Gunning, William T., Dube, Prabhatchandra, Kleinhenz, Andrew L., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894821/
https://ncbi.nlm.nih.gov/pubmed/31805072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225604
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