Wharton’s jelly mesenchymal stem cell-based or umbilical vein endothelial cell-based serum-free coculture with cytokines supports the ex vivo expansion/maintenance of cord blood hematopoietic stem/progenitor cells

BACKGROUND: The umbilical cord blood (UCB) has been widely accepted as an alternative source of hematopoietic stem/progenitor cells (HSPCs) for transplantation, and its use in adults is still restricted because of low absolute numbers. To overcome this obstacle, expansion of UCB-HSPCs under feeder c...

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Publicat a:Stem Cell Res Ther
Autors principals: Li, Qiuyang, Zhao, Dewan, Chen, Qiang, Luo, Maowen, Huang, Jingcao, Yang, Cao, Wang, Fangfang, Li, Wenxian, Liu, Ting
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894464/
https://ncbi.nlm.nih.gov/pubmed/31806004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1502-8
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