Hypoxia with Wharton’s jelly mesenchymal stem cell coculture maintains stemness of umbilical cord blood-derived CD34(+) cells

BACKGROUND: The physiological approach suggests that an environment associating mesenchymal stromal cells with low O(2) concentration would be most favorable for the maintenance of hematopoietic stem/progenitor cells (HSPCs). To test this hypothesis, we performed a coculture of cord blood CD34(+) ce...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Zhao, Dewan, Liu, Lingjia, Chen, Qiang, Wang, Fangfang, Li, Qiuyang, Zeng, Qiang, Huang, Jingcao, Luo, Maowen, Li, Wenxian, Zheng, Yuhuan, Liu, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998541/
https://ncbi.nlm.nih.gov/pubmed/29895317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0902-5
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