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Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice

BACKGROUND: Cigarette smoke (CS)-induced lung inflammation and Chronic Obstructive Pulmonary disease (COPD) involves mitochondrial dysfunction. Mesenchymal stem cells (MSC) and MSC-derived exosomes (EXO) are reported to show therapeutic effects in many animal models of inflammation and injury. In th...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Maremanda, Krishna Prahlad, Sundar, Isaac K., Rahman, Irfan
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894395/
https://ncbi.nlm.nih.gov/pubmed/31678243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.114788
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