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Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury

Antagonism of CXCR2 receptors, predominately located on neutrophils and critical for their immunomodulatory activity, is an attractive pharmacological therapeutic approach aimed at reducing the potentially damaging effects of heightened neutrophil influx into the lung. The role CXCR2 in lung inflamm...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lerner, Chad A., Lei, Wei, Sundar, Isaac K., Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078490/
https://ncbi.nlm.nih.gov/pubmed/27826243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00391
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