N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl–coenzyme A and aspartate. In the brain, NAA is considered an important energy metabolite for lipid synthesis. However, the role of NAA in peripheral tissues remained elusive. Therefore, we characterized...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Hofer, Dina C., Zirkovits, Gabriel, Pelzmann, Helmut J., Huber, Katharina, Pessentheiner, Ariane R., Xia, Wenmin, Uno, Kyosuke, Miyazaki, Toh, Kon, Kanta, Tsuneki, Hiroshi, Pendl, Tobias, Al Zoughbi, Wael, Madreiter-Sokolowski, Corina T., Trausinger, Gert, Abdellatif, Mahmoud, Schoiswohl, Gabriele, Schreiber, Renate, Eisenberg, Tobias, Magnes, Christoph, Sedej, Simon, Eckhardt, Matthias, Sasahara, Masakiyo, Sasaoka, Toshiyasu, Nitta, Atsumi, Hoefler, Gerald, Graier, Wolfgang F., Kratky, Dagmar, Auwerx, Johan, Bogner-Strauss, Juliane G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894082/
https://ncbi.nlm.nih.gov/pubmed/31638418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801323R
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