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Complexes formed with integrin-α5 and KCNB1 potassium channel wild type or epilepsy-susceptibility variants modulate cellular plasticity via Ras and Akt signaling
Voltage-gated potassium (K(+)) channel subfamily B member 1 (KCNB1, Kv2.1) and integrin-α5 form macromolecular complexes—named integrin-α5-KCNB1 complexes (IKCs)—in the human brain, but their function was poorly understood. Here we report that membrane depolarization triggered IKC intracellular sign...
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| Publicado no: | FASEB J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6894052/ https://ncbi.nlm.nih.gov/pubmed/31682765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901792R |
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