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Cytosolic phospholipase A2 is a key regulator of blood–brain barrier function in epilepsy

Blood–brain barrier dysfunction in epilepsy contributes to seizures and resistance to antiseizure drugs. Reports show that seizures increase brain glutamate levels, leading to barrier dysfunction. One component of barrier dysfunction is overexpression of the drug efflux transporters P-glycoprotein (...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Hartz, Anika M. S., Rempe, Ralf G., Soldner, Emma L. B., Pekcec, Anton, Schlichtiger, Juli, Kryscio, Richard, Bauer, Bjoern
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894050/
https://ncbi.nlm.nih.gov/pubmed/31661303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901369RR
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