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P-gp Protein Expression and Transport Activity in Rodent Seizure Models and Human Epilepsy

A cure for epilepsy is currently not available, and seizure genesis, seizure recurrence, and resistance to antiseizure drugs remain serious clinical problems. Studies show that the blood–brain barrier is altered in animal models of epilepsy and in epileptic patients. In this regard, seizures increas...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Hartz, Anika M. S., Pekcec, Anton, Soldner, Emma L. B., Zhong, Yu, Schlichtiger, Juli, Bauer, Bjoern
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498434/
https://ncbi.nlm.nih.gov/pubmed/28195743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00770
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