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P-gp Protein Expression and Transport Activity in Rodent Seizure Models and Human Epilepsy

A cure for epilepsy is currently not available, and seizure genesis, seizure recurrence, and resistance to antiseizure drugs remain serious clinical problems. Studies show that the blood–brain barrier is altered in animal models of epilepsy and in epileptic patients. In this regard, seizures increas...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Hartz, Anika M. S., Pekcec, Anton, Soldner, Emma L. B., Zhong, Yu, Schlichtiger, Juli, Bauer, Bjoern
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498434/
https://ncbi.nlm.nih.gov/pubmed/28195743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00770
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