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Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
BACKGROUND: Plasma cells (PCs) are terminally differentiated B-lymphocytes producing antibodies. In coeliac disease (CeD) there is increased density of PCs in the small-intestinal lesion. Many of these PCs produce disease-specific autoantibodies targeting transglutaminase 2 (TG2). OBJECTIVE: The pla...
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| Pubblicato in: | United European Gastroenterol J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893993/ https://ncbi.nlm.nih.gov/pubmed/31839965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640619862461 |
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