Antibody-secreting plasma cells persist for decades in human intestine

Plasma cells (PCs) produce antibodies that mediate immunity after infection or vaccination. In contrast to PCs in the bone marrow, PCs in the gut have been considered short lived. In this study, we studied PC dynamics in the human small intestine by cell-turnover analysis in organ transplants and by...

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Publicado en:J Exp Med
Autores principales: Landsverk, Ole J.B., Snir, Omri, Casado, Raquel Bartolomé, Richter, Lisa, Mold, Jeff E., Réu, Pedro, Horneland, Rune, Paulsen, Vemund, Yaqub, Sheraz, Aandahl, Einar Martin, Øyen, Ole M., Thorarensen, Hildur Sif, Salehpour, Mehran, Possnert, Göran, Frisén, Jonas, Sollid, Ludvig M., Baekkevold, Espen S., Jahnsen, Frode L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294861/
https://ncbi.nlm.nih.gov/pubmed/28104812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161590
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