Antibody-secreting plasma cells persist for decades in human intestine

Plasma cells (PCs) produce antibodies that mediate immunity after infection or vaccination. In contrast to PCs in the bone marrow, PCs in the gut have been considered short lived. In this study, we studied PC dynamics in the human small intestine by cell-turnover analysis in organ transplants and by...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Landsverk, Ole J.B., Snir, Omri, Casado, Raquel Bartolomé, Richter, Lisa, Mold, Jeff E., Réu, Pedro, Horneland, Rune, Paulsen, Vemund, Yaqub, Sheraz, Aandahl, Einar Martin, Øyen, Ole M., Thorarensen, Hildur Sif, Salehpour, Mehran, Possnert, Göran, Frisén, Jonas, Sollid, Ludvig M., Baekkevold, Espen S., Jahnsen, Frode L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294861/
https://ncbi.nlm.nih.gov/pubmed/28104812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161590
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