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Epigenetic Activation of BRCA1 by Genistein In Vivo and Triple Negative Breast Cancer Cells Linked to Antagonism toward Aryl Hydrocarbon Receptor

Triple negative breast cancers (TNBC) are the most aggressive and lethal breast cancers (BC). The aryl hydrocarbon receptor (AHR) is often overexpressed in TNBC, and its activation results in the epigenetic silencing of BRCA1, which is a necessary factor for the transcriptional activation of estroge...

詳細記述

保存先:
書誌詳細
出版年:Nutrients
主要な著者: Donovan, Micah G., Selmin, Ornella I., Doetschman, Thomas C., Romagnolo, Donato F.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893467/
https://ncbi.nlm.nih.gov/pubmed/31652854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11112559
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