Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress

Excessive compression, the main cause of intervertebral disc (IVD) degeneration, affected endogenous repair of the intervertebral disc. Pioglitazone (PGZ) is the agonist of peroxisome proliferator-activated receptor γ, which has been widely used in the treatment of diabetes mellitus. The present stu...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Hu, Yiqiang, Huang, Liang, Shen, Min, Liu, Yunlu, Liu, Guohui, Wu, Yongchao, Ding, Fan, Ma, Kaige, Wang, Wentian, Zhang, Yanbin, Shao, Zengwu, Cai, Xianyi, Xiong, Liming
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893265/
https://ncbi.nlm.nih.gov/pubmed/31885796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4764071
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