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Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress

Excessive compression, the main cause of intervertebral disc (IVD) degeneration, affected endogenous repair of the intervertebral disc. Pioglitazone (PGZ) is the agonist of peroxisome proliferator-activated receptor γ, which has been widely used in the treatment of diabetes mellitus. The present stu...

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Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Hu, Yiqiang, Huang, Liang, Shen, Min, Liu, Yunlu, Liu, Guohui, Wu, Yongchao, Ding, Fan, Ma, Kaige, Wang, Wentian, Zhang, Yanbin, Shao, Zengwu, Cai, Xianyi, Xiong, Liming
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893265/
https://ncbi.nlm.nih.gov/pubmed/31885796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4764071
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