Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway

OBJECTIVE: Excessive apoptosis of nucleus pulposus cells (NPCs) induced by various stresses, including compression, contributes to the development of intervertebral disc degeneration (IVDD). Mesenchymal stem cells (MSCs) can benefit the regeneration of NPCs and delay IVDD, but the underlying molecul...

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Foilsithe in:Stem Cells Int
Main Authors: Chen, Sheng, Zhao, Lei, Deng, Xiangyu, Shi, Deyao, Wu, Fashuai, Liang, Hang, Huang, Donghua, Shao, Zengwu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://ncbi.nlm.nih.gov/pubmed/29387092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9843120
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