Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway

OBJECTIVE: Excessive apoptosis of nucleus pulposus cells (NPCs) induced by various stresses, including compression, contributes to the development of intervertebral disc degeneration (IVDD). Mesenchymal stem cells (MSCs) can benefit the regeneration of NPCs and delay IVDD, but the underlying molecul...

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Bibliographic Details
Published in:Stem Cells Int
Main Authors: Chen, Sheng, Zhao, Lei, Deng, Xiangyu, Shi, Deyao, Wu, Fashuai, Liang, Hang, Huang, Donghua, Shao, Zengwu
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://ncbi.nlm.nih.gov/pubmed/29387092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9843120
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