Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway

OBJECTIVE: Excessive apoptosis of nucleus pulposus cells (NPCs) induced by various stresses, including compression, contributes to the development of intervertebral disc degeneration (IVDD). Mesenchymal stem cells (MSCs) can benefit the regeneration of NPCs and delay IVDD, but the underlying molecul...

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Vydáno v:Stem Cells Int
Hlavní autoři: Chen, Sheng, Zhao, Lei, Deng, Xiangyu, Shi, Deyao, Wu, Fashuai, Liang, Hang, Huang, Donghua, Shao, Zengwu
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://ncbi.nlm.nih.gov/pubmed/29387092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9843120
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