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Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway

OBJECTIVE: Excessive apoptosis of nucleus pulposus cells (NPCs) induced by various stresses, including compression, contributes to the development of intervertebral disc degeneration (IVDD). Mesenchymal stem cells (MSCs) can benefit the regeneration of NPCs and delay IVDD, but the underlying molecul...

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書目詳細資料
發表在:Stem Cells Int
Main Authors: Chen, Sheng, Zhao, Lei, Deng, Xiangyu, Shi, Deyao, Wu, Fashuai, Liang, Hang, Huang, Donghua, Shao, Zengwu
格式: Artigo
語言:Inglês
出版: Hindawi 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://ncbi.nlm.nih.gov/pubmed/29387092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9843120
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