Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast

Precise allele replacement (genome editing), without unwanted changes to the genome, provides a powerful tool to define the functions of DNA elements and encoded factors in their normal biological context. While CRISPR is now used extensively for gene targeting, its utility for precise allele replac...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:G3 (Bethesda)
Asıl Yazarlar: Storey, Aaron J., Wang, Hsin-Ping, Protacio, Reine U., Davidson, Mari K., Wahls, Wayne P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2019
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893178/
https://ncbi.nlm.nih.gov/pubmed/31597677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400805
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