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Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast

Precise allele replacement (genome editing), without unwanted changes to the genome, provides a powerful tool to define the functions of DNA elements and encoded factors in their normal biological context. While CRISPR is now used extensively for gene targeting, its utility for precise allele replac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:G3 (Bethesda)
मुख्य लेखकों: Storey, Aaron J., Wang, Hsin-Ping, Protacio, Reine U., Davidson, Mari K., Wahls, Wayne P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Genetics Society of America 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893178/
https://ncbi.nlm.nih.gov/pubmed/31597677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400805
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