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High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell

Single-cell RNA sequencing can reveal the transcriptional state of cells, yet provides little insight into the upstream regulatory landscape associated with open or accessible chromatin regions. Joint profiling of accessible chromatin and RNA within the same cells would permit direct matching of tra...

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Dades bibliogràfiques
Publicat a:Nat Biotechnol
Autors principals: Chen, Song, Lake, Blue B, Zhang, Kun
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893138/
https://ncbi.nlm.nih.gov/pubmed/31611697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0290-0
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