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High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell

Single-cell RNA sequencing can reveal the transcriptional state of cells, yet provides little insight into the upstream regulatory landscape associated with open or accessible chromatin regions. Joint profiling of accessible chromatin and RNA within the same cells would permit direct matching of tra...

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Bibliografiske detaljer
Udgivet i:Nat Biotechnol
Main Authors: Chen, Song, Lake, Blue B, Zhang, Kun
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893138/
https://ncbi.nlm.nih.gov/pubmed/31611697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0290-0
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