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An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Simultaneous profiling of transcriptome and chromatin accessibility within single cells is a powerful approach to dissect gene regulatory programs in complex tissues. However, the current tools are limited by modest throughput. We now describe an ultra high-throughput method, Paired-seq, for paralle...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Zhu, Chenxu, Yu, Miao, Huang, Hui, Juric, Ivan, Abnousi, Armen, Hu, Rong, Lucero, Jacinta, Behrens, M. Margarita, Hu, Ming, Ren, Bing
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231560/
https://ncbi.nlm.nih.gov/pubmed/31695190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0323-x
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